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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIVEP2 All Species: 11.82
Human Site: T1249 Identified Species: 32.5
UniProt: P31629 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31629 NP_006725.3 2446 269053 T1249 Y G K P S F Q T E I H S S Y P
Chimpanzee Pan troglodytes XP_518773 2611 286870 T1414 Y G K P S F Q T E I H S S Y P
Rhesus Macaque Macaca mulatta XP_001092694 2411 264713 T1214 Y G K P S F Q T E I H S S Y P
Dog Lupus familis XP_850296 2435 267534 A1244 Y G K P S F Q A E I H P G Y P
Cat Felis silvestris
Mouse Mus musculus Q3UHF7 2430 266686 A1237 Y S K P P F Q A D L H S S Y P
Rat Rattus norvegicus Q00900 2437 267408 D1244 S K P P F Q A D I H S S Y S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507497 2629 288405 P1431 Y V R S P F Q P E L H T G Y H
Chicken Gallus gallus XP_419711 2470 273534 T1268 Y V K Q P F Q T D I P P S Y H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001025335 2298 253367 I1169 P Y Q P S H Q I Q V Q T D S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.3 93.3 91.9 N.A. 87.2 87.5 N.A. 74 73.8 N.A. 46.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 93.4 93.9 94.4 N.A. 92 92 N.A. 79.9 82.4 N.A. 59.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 66.6 13.3 N.A. 40 53.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 80 13.3 N.A. 60 60 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 12 23 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 23 0 0 0 12 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 56 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 12 78 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 45 0 0 0 0 0 0 0 0 0 0 23 0 0 % G
% His: 0 0 0 0 0 12 0 0 0 12 67 0 0 0 23 % H
% Ile: 0 0 0 0 0 0 0 12 12 56 0 0 0 0 0 % I
% Lys: 0 12 67 0 0 0 0 0 0 0 0 0 0 0 12 % K
% Leu: 0 0 0 0 0 0 0 0 0 23 0 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 0 12 78 34 0 0 12 0 0 12 23 0 0 56 % P
% Gln: 0 0 12 12 0 12 89 0 12 0 12 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 12 0 12 56 0 0 0 0 0 12 56 56 23 0 % S
% Thr: 0 0 0 0 0 0 0 45 0 0 0 23 0 0 0 % T
% Val: 0 23 0 0 0 0 0 0 0 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 78 12 0 0 0 0 0 0 0 0 0 0 12 78 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _